About “GOOD ON” TIME
Are you optimizing your “Good On” time* with your current PD treatment?
Understanding the ups and downs of IR CD/LD
LAURA,
on CREXONT since 2024
LEVODOPA LEVELS
Do you notice ups and downs with your IR CD/LD?
IR CD/LD has been the standard of care for treating PD for many years—it’s designed to work quickly but may wear off quickly too.
Ups and downs of IR CD/LD
Dyskinesia
Dyskinesia happens when your medicine is working, but the level of levodopa is too high and you may experience movements you can’t control
“Good On” time and “On” time
“Good On” time is when your medicine is working, and you are not experiencing dyskinesia or it is not troubling you.
“On” time is when your medicine is working and your symptoms are well-controlled, but you may be experiencing troublesome dyskinesia
“Off” time
“Off” time is when your medicine is not working and symptoms return
Dyskinesia
Dyskinesia happens when your medicine is working, but the level of levodopa is too high and you may experience movements you can’t control
“Good On” time and “On” time
“Good On” time is when your medicine is working, and you are not experiencing dyskinesia or it is not troubling you.
“On” time is when your medicine is working and your symptoms are well-controlled, but you may be experiencing troublesome dyskinesia
“Off” time
“Off” time is when your medicine is not working and symptoms return

Over time with IR CD/LD, the duration of your symptom control may become more unpredictable, and you may experience more “Off” time. In fact, about half of patients taking a PD medication may experience “Off” episodes within 2 to 3 years of being on treatment
Tracking your “Good On” time* could be helpful
If you are noticing fluctuations with your IR CD/LD treatment, it could be helpful to track your “Good On” time*, “On” time, and “Off” time after each dose.
This information can not only be helpful for you, but it can also provide essential information when speaking with your doctor.
Footnotes
*“Good On” time is defined as “On” time without troublesome dyskinesia.